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Literature summary for 7.2.2.9 extracted from

  • Osman, D.; Patterson, C.; Bailey, K.; Fisher, K.; Robinson, N.; Rigby, S.; Cavet, J.
    The copper supply pathway to a Salmonella Cu,Zn-superoxide dismutase (SodCII) involves P1B-type ATPase copper efflux and periplasmic CueP (2013), Mol. Microbiol., 87, 466-477.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhimurium
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Salmonella enterica subsp. enterica serovar Typhimurium A0A0H3NA56
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Salmonella enterica subsp. enterica serovar Typhimurium SL1344
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Salmonella enterica subsp. enterica serovar Typhimurium SL1344 A0A0H3NA56
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Synonyms

Synonyms Comment Organism
CopA
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Salmonella enterica subsp. enterica serovar Typhimurium
GolT
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Salmonella enterica subsp. enterica serovar Typhimurium

General Information

General Information Comment Organism
physiological function either of P1B-type ATPases, CopA or GolT, is needed to activate periplasmic Cu,Zn-superoxide dismutase. A CopA/GolT double mutant accumulates inactive Cu,Zn-superoxide dismutase which can be activated by copper-supplementation in vitro. In contrast, either single ATPase mutant accumulates fully active Cu,Zn-superoxide dismutase Salmonella enterica subsp. enterica serovar Typhimurium