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Literature summary for 7.2.2.9 extracted from
- Plastocyanin controls the stabilization of the thylakoid Cu-transporting P-type ATPase PAA2/HMA8 in response to low copper in Arabidopsis (2012), J. Biol. Chem., 287, 18544-18550.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| chloroplast | - |
Arabidopsis thaliana | 9507 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | B9DFX7 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PAA2/HMA8 | - |
Arabidopsis thaliana |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Arabidopsis thaliana | isoform PAA2 protein abundance decreases significantly and specifically when Cu in the media is increased. Copper addition does not affect PAA2 transcript levels, but stability of the PAA2 protein is decreased in plants grown with elevated copper levels | down |
| Arabidopsis thaliana | PAA2 protein abundance is significantly increased in paa1 mutants, in which the copper content in the chloroplast is half of that of the wild-type, due to impaired copper import into the organelle. In a pc2 insertion mutant, which has strongly reduced plastocyanin expression, the PAA2 protein levels are low regardless of copper addition to the growth media | additional information |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | plastid copper levels control PAA2 stability. Plastocyanin, which is the target of PAA2 mediated copper delivery in thylakoids, is a major determinant of this regulatory mechanism | Arabidopsis thaliana |
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