Literature summary for 7.2.2.9 extracted from

DeSilva, T.M.; Veglia, G.; Opella, S.J.
Solution structures of the reduced and Cu(I) bound forms of the first metal binding sequence of ATP7A associated with Menkes disease (2005), Proteins, 61, 1038-1049.

Search for more literature for 7.2.2.9

Cloned(Commentary)

Cloned (Comment)	Organism
expression of a chimeric metal bidnding sequence with the Menkes disease protein carrying the binding motif of bacterial Hg(II) binding protein MerP. This chimeric protein shows differences in structure and the dynamics of the binding site that may account for metal specificity	Homo sapiens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
additional information	solution structure of the reduced and Cu(I) bound forms of the first metal binding sequence of ATP7A. The XMTCXXC sequence may play a prominent role in the dynamics of the metal bidning loop. the residues of the metal binding loop may transduce slight changes in the tertiary fold of the protein that account for metal specificity in Cu(I) bound MNK1	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q04656	-	-

Synonyms

Synonyms	Comment	Organism
ATP7A	-	Homo sapiens
Menkes disease protein	-	Homo sapiens
MNK1	-	Homo sapiens

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Release 2023.1 (January 2023)