Literature summary for 7.2.2.9 extracted from

Sugeno, H.; Takebayashi, Y.; Higashimoto, M.; Ogura, Y.; Shibukawa, G.; Kanzaki, A.; Terada, K.; Sugiyama, T.; Watanabe, K.; Katoh, R.; Nitta, Y.; Fukushima, T.; Koyama, Y.; Inoue, N.; Sekikawa, K.; Ogawa, K.; Sato, Y.; Takenoshita, S.
Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) in human hepatocellular carcinoma (2004), Anticancer Res., 24, 1045-1048.

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Application

Application	Comment	Organism
medicine	the overexpression of ATP7B in hepatocellular carcinoma might be associated with unfavorable clinical outcome in patients treated with cisplantin-based chemotherapy. Analysis of ATP7B expression might be clinically relevant for the choice of therapy	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P35670	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
bile duct	ATP7B is expressed in bile duct epithelial cells, where it may mediate copper secretion into bile fluid	Homo sapiens	-
hepatocellular carcinoma cell	the overexpression of ATP7B in hepatocellular carcinoma might be associated with unfavorable clinical outcome in patients treated with cisplantin-based chemotherapy	Homo sapiens	-
additional information	no ATP7B expression in normal hepatic cells	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
ATP7B	-	Homo sapiens

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Release 2023.1 (January 2023)