Literature summary for 7.2.2.8 extracted from

Yang, Y.; Mandal, A.K.; Bredeston, L.M.; Gonzalez-Flecha, F.L.; Argueello, J.M.
Activation of Archaeoglobus fulgidus Cu(+)-ATPase CopA by cysteine (2007), Biochim. Biophys. Acta, 1768, 495-501.

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Activating Compound

Activating Compound	Comment	Organism	Structure
Cys	millimolar concentration of Cys increase the activity about 800fold. Cys is a non-essential activator of the enzyme, interacting with the cytoplasmic side of the enzyme. K1/2 of 4 mM	Archaeoglobus fulgidus

Organism

Organism	UniProt	Comment	Textmining
Archaeoglobus fulgidus	O29777	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + Ag+[side 1]	-	Archaeoglobus fulgidus	ADP + phosphate + Ag+[side 2]	-	?
ATP + H2O + Cu+[side 1]	-	Archaeoglobus fulgidus	ADP + phosphate + Cu+[side 2]	-	?

Synonyms

Synonyms	Comment	Organism
CopA	-	Archaeoglobus fulgidus

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
75	-	assay at	Archaeoglobus fulgidus

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
6.1	-	assay at	Archaeoglobus fulgidus

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Release 2023.1 (January 2023)