Literature summary for 7.2.2.7 extracted from

Weaver, K.D.; Heymann, J.J.; Mehta, A.; Roulhac, P.L.; Anderson, D.S.; Nowalk, A.J.; Adhikari, P.; Mietzner, T.A.; Fitzgerald, M.C.; Crumbliss, A.L.
Ga(3+) as a mechanistic probe in Fe(3+) transport - characterization of Ga (3+) interaction with FbpA (2008), J. Biol. Inorg. Chem., 13, 887-898.

Search for more literature for 7.2.2.7

Cloned(Commentary)

Cloned (Comment)	Organism
the FbpA gene from Neisseria gonorrhoeae strain F62 is cloned for expression of the protein in Escherichia coli cells	Neisseria gonorrhoeae

Inhibitors

Inhibitors	Comment	Organism	Structure
Ga3+	-	Haemophilus influenzae
gallium	-	Neisseria gonorrhoeae
gallium	-	Neisseria meningitidis

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
34000	-	FbpA	Haemophilus influenzae
34000	-	FbpA	Neisseria gonorrhoeae
34000	-	FbpA	Neisseria meningitidis

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + Fe3+/out	Haemophilus influenzae	shuttling of free Fe3+ through the periplasm	ADP + phosphate + Fe3+/in	-	?
ATP + H2O + Fe3+/out	Neisseria gonorrhoeae	shuttling of free Fe3+ through the periplasm	ADP + phosphate + Fe3+/in	-	?
ATP + H2O + Fe3+/out	Neisseria meningitidis	shuttling of free Fe3+ through the periplasm	ADP + phosphate + Fe3+/in	-	?

Organism

Organism	UniProt	Comment	Textmining
Haemophilus influenzae	-	-	-
Neisseria gonorrhoeae	-	-	-
Neisseria meningitidis	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
apo-FbpA is purified by cetyltrimethylammonium bromide extraction and by using a carboxymethyl Sepharose column	Neisseria gonorrhoeae

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + Fe3+/out	shuttling of free Fe3+ through the periplasm	Haemophilus influenzae	ADP + phosphate + Fe3+/in	-	?
ATP + H2O + Fe3+/out	shuttling of free Fe3+ through the periplasm	Neisseria gonorrhoeae	ADP + phosphate + Fe3+/in	-	?
ATP + H2O + Fe3+/out	shuttling of free Fe3+ through the periplasm	Neisseria meningitidis	ADP + phosphate + Fe3+/in	-	?

Synonyms

Synonyms	Comment	Organism
Fe3+transporting ATPase	-	Haemophilus influenzae
Fe3+transporting ATPase	-	Neisseria gonorrhoeae
Fe3+transporting ATPase	-	Neisseria meningitidis
hFbpABC transporter	-	Haemophilus influenzae
hFbpABC transporter	-	Neisseria gonorrhoeae
hFbpABC transporter	-	Neisseria meningitidis

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Release 2023.1 (January 2023)