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Literature summary for 7.2.2.4 extracted from

  • Cheng, J.; Guffanti, A.; Krulwich, T.
    A two-gene ABC-type transport system that extrudes Na+ in Bacillus subtilis is induced by ethanol or protonophore (1997), Mol. Microbiol., 23, 1107-1120 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli EP432 cells Bacillus subtilis

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Bacillus subtilis 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Na+[side 1] Bacillus subtilis the enzyme is an inducible, ABC transport system that catalyses ATP-dependent electrogenic Na+ extrusion without mechanistically coupled proton or K+ uptake ADP + phosphate + Na+[side 2]
-
?
ATP + H2O + Na+[side 1] Bacillus subtilis BD99 the enzyme is an inducible, ABC transport system that catalyses ATP-dependent electrogenic Na+ extrusion without mechanistically coupled proton or K+ uptake ADP + phosphate + Na+[side 2]
-
?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis P46903
-
-
Bacillus subtilis P46904
-
-
Bacillus subtilis BD99 P46903
-
-
Bacillus subtilis BD99 P46904
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Na+[side 1]
-
Bacillus subtilis ADP + phosphate + Na+[side 2]
-
?
ATP + H2O + Na+[side 1] the enzyme is an inducible, ABC transport system that catalyses ATP-dependent electrogenic Na+ extrusion without mechanistically coupled proton or K+ uptake Bacillus subtilis ADP + phosphate + Na+[side 2]
-
?
ATP + H2O + Na+[side 1]
-
Bacillus subtilis BD99 ADP + phosphate + Na+[side 2]
-
?
ATP + H2O + Na+[side 1] the enzyme is an inducible, ABC transport system that catalyses ATP-dependent electrogenic Na+ extrusion without mechanistically coupled proton or K+ uptake Bacillus subtilis BD99 ADP + phosphate + Na+[side 2]
-
?
ATP + H2O + Rb+[side 1]
-
Bacillus subtilis ADP + phosphate + Rb+[side 2]
-
?
ATP + H2O + Rb+[side 1]
-
Bacillus subtilis BD99 ADP + phosphate + Rb+[side 2]
-
?

Synonyms

Synonyms Comment Organism
NatA
-
Bacillus subtilis
natAB operon name Bacillus subtilis
natB
-
Bacillus subtilis

Expression

Organism Comment Expression
Bacillus subtilis expression of the operon is induced by ethanol and the carbonylcyanide p-chlorophenylhydrazone, and, more modestly, by Na+, and K+, but not by choline or a high concentration of sucrose up