Any feedback?
Literature summary for 7.2.2.3 extracted from
- Signaling pathways involving the sodium pump stimulate NO production in endothelial cells (2006), Biochim. Biophys. Acta, 1758, 1809-1814.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | enzyme is involved in vascular tone regulation | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ouabain | binding of inhibitor to enzyme results in activation of the proliferation and survival pathways involving PI3K, Akt activation, stimulation of eNOS, and production of NO in human umbilical cord endothelial cells | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| endothelial cell | HUAEC cell, human umbilical cord endothelial cell | Homo sapiens | - |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
