Protein Variants | Comment | Organism |
---|---|---|
A910G | mutants more sensitive to Cd2+ than wild type strain, higher activity for glutathione S-conjugated leukotriene C4 | Saccharomyces cerevisiae |
D777N | mutants exhibit a Cd2+ hypersensitive phenotype, partially reduced transport activity for glutathione S-conjugated leukotriene C4 | Saccharomyces cerevisiae |
D821G | mutants with Ycf1p in vivo activity as wild type strain | Saccharomyces cerevisiae |
E709Q | mutants with Ycf1p in vivo activity as wild type strain | Saccharomyces cerevisiae |
E927K | mutants exhibit a Cd2+ hypersensitive phenotype | Saccharomyces cerevisiae |
G1306E | mutants exhibit a Cd2+ hypersensitive phenotype, abolished transport activity for glutathione S-conjugated leukotriene C4 | Saccharomyces cerevisiae |
G1311R | mutants exhibit a Cd2+ hypersensitive phenotype, abolished transport activity for glutathione S-conjugated leukotriene C4 | Saccharomyces cerevisiae |
G1413D | mutants exhibit a Cd2+ hypersensitive phenotype | Saccharomyces cerevisiae |
G663V | mutants exhibit a Cd2+ hypersensitive phenotype, abolished transport activity for glutathione S-conjugated leukotriene C4 | Saccharomyces cerevisiae |
G756D | mutants exhibit a Cd2+ hypersensitive phenotype, abolished transport activity for glutathione S-conjugated leukotriene C4 | Saccharomyces cerevisiae |
G835R | mutants more sensitive to Cd2+ than wild type strain, partially reduced transport activity for glutathione S-conjugated leukotriene C4 | Saccharomyces cerevisiae |
I711S | mutants exhibit a Cd2+ hypersensitive phenotype | Saccharomyces cerevisiae |
I840P | mutants more sensitive to Cd2+ than wild type strain, partially reduced transport activity for glutathione S-conjugated leukotriene C4 | Saccharomyces cerevisiae |
L817S | mutants more sensitive to Cd2+ than wild type strain | Saccharomyces cerevisiae |
L825T | mutants more sensitive to Cd2+ than wild type strain | Saccharomyces cerevisiae |
L826S | mutants more sensitive to Cd2+ than wild type strain, partially reduced transport activity for glutathione S-conjugated leukotriene C4 | Saccharomyces cerevisiae |
additional information | deletion of L712 and F713, mutants exhibit a Cd2+ hypersensitive phenotype | Saccharomyces cerevisiae |
N1366K | mutants exhibit a Cd2+ hypersensitive phenotype, partially reduced transport activity for glutathione S-conjugated leukotriene C4 | Saccharomyces cerevisiae |
Q1148P | mutants more sensitive to Cd2+ than wild type strain | Saccharomyces cerevisiae |
R1143C | mutants more sensitive to Cd2+ than wild type strain, partially reduced transport activity for glutathione S-conjugated leukotriene C4 | Saccharomyces cerevisiae |
Y855L | mutants more sensitive to Cd2+ than wild type strain, higher activity for glutathione S-conjugated leukotriene C4 | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
tonoplast | - |
Saccharomyces cerevisiae | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Cd/cytoplasm + ATP + H2O | Saccharomyces cerevisiae | - |
Cd/vacuole + ADP + phosphate | - |
? | |
glutathione S-conjugated leukotriene C4/cytoplasm + ATP + H2O | Saccharomyces cerevisiae | - |
glutathione S-conjugated leukotriene C4/vacuole + ADP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Cd/cytoplasm + ATP + H2O | - |
Saccharomyces cerevisiae | Cd/vacuole + ADP + phosphate | - |
? | |
glutathione S-conjugated leukotriene C4/cytoplasm + ATP + H2O | - |
Saccharomyces cerevisiae | glutathione S-conjugated leukotriene C4/vacuole + ADP + phosphate | - |
? |