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Literature summary for 7.2.2.19 extracted from

  • Jana, K.; Bandyopadhyay, T.; Ganguly, B.
    Designed inhibitors with hetero linkers for gastric proton pump H+,K+-ATPase Steered molecular dynamics and metadynamics studies (2017), J. Mol. Graph. Model., 78, 129-138 .
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
SCH28080 i.e., 2-methyl-8-(phenylmethoxy)imidazo[1,2-a]pyridine-3-acetonitrile Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + H+[side 1] + K+[side 2] Sus scrofa
-
ADP + phosphate + H+[side 2] + K+[side 1]
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa P19156 and P18434 subunits alpha and beta
-

Source Tissue

Source Tissue Comment Organism Textmining
stomach
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + H+[side 1] + K+[side 2]
-
Sus scrofa ADP + phosphate + H+[side 2] + K+[side 1]
-
?

Synonyms

Synonyms Comment Organism
H+,K+-ATPase
-
Sus scrofa