Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 7.2.2.19 extracted from

  • Wang, J.; Barbuskaite, D.; Tozzi, M.; Giannuzzo, A.; Sorensen, C.E.; Novak, I.
    Proton pump inhibitors inhibit pancreatic secretion: role of gastric and non-gastric H+/K+-ATPases (2015), PLoS ONE, 10, e0126432.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.2.2.19

Inhibitors

Inhibitors Comment Organism Structure
Omeprazole
-
 Homo sapiens
SCH28080
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35000
-
 x * 35000, subunit HKbeta, SDS-PAGE Homo sapiens
100000
-
 x * 100000, subunit HKalpha2, SDS-PAGE Homo sapiens
115000
-
 x * 115000, subunit HKalpha1, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + H+/in + K+/out Homo sapiens
-
 ADP + phosphate + H+/out + K+/in
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
CAPAN-1 cell
-
 Homo sapiens
-
pancreas
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + H+/in + K+/out
-
 Homo sapiens ADP + phosphate + H+/out + K+/in
-
 ?

Subunits

Subunits Comment Organism
? x * 100000, subunit HKalpha2, SDS-PAGE Homo sapiens
? x * 115000, subunit HKalpha1, SDS-PAGE Homo sapiens
? x * 35000, subunit HKbeta, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
H+/K+ pump
-
 Homo sapiens
H+/K+-ATPase
-
 Homo sapiens
HKalpha1 gastric alpha subunit Homo sapiens
HKalpha2 non-gastric alpha subunit Homo sapiens
HKbeta gastric beta subunit Homo sapiens