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Literature summary for 7.2.2.19 extracted from

  • Liu, J.; Huang, N.; Li, N.; Liu, S.; Li, M.; Li, H.; Luo, X.; Wang, Y.; Li, L.; Zou, Q.; Liu, Y.; Yang, T.
    2-(1H-benzimidazol-2-yl)-4,5,6,7-tetrahydro-2H-indazol-3-ol, a benzimidazole derivative, inhibits T cell proliferation involving H+/K+-ATPase inhibition (2014), Molecules, 19, 17173-17186.
    View publication on PubMedView publication on EuropePMC
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Inhibitors

Inhibitors Comment Organism Structure
BMT-1 i.e. 2-(1H-benzimidazol-2-yl)-4,5,6,7-tetrahydro-2H-indazol-3-ol Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
70000
-
 x * 70000, beta-subunit ATP4B, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + H+/in + K+/out Homo sapiens
-
 ADP + phosphate + H+/out + K+/in
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
T-cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + H+/in + K+/out
-
 Homo sapiens ADP + phosphate + H+/out + K+/in
-
 ?

Subunits

Subunits Comment Organism
? x * 70000, beta-subunit ATP4B, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
ATP4B H+/K+-ATPase beta-subunit Homo sapiens
H+,K+-ATPase
-
 Homo sapiens