Any feedback?
Literature summary for 7.2.2.19 extracted from
- Differences in binding properties of two proton pump inhibitors on the gastric H(+),K(+)-ATPase in vivo (2004), Biochem. Pharmacol., 68, 2117-2127.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Omeprazole | binding at Cys813 and Cys892 is reversible both in vivo and in vitro | Rattus norvegicus |  |
| pantoprazole | binding at Cys822 is irreversible | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + H+/in + K+/out | - |
Rattus norvegicus | ADP + phosphate + H+/out + K+/in | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| H(+),K(+)-ATPase | - |
Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
