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Literature summary for 7.2.2.19 extracted from

  • Hango, T.; Nojima, S.; Setaka, M.
    Purification and characterization of (H+ + K+)-ATPase from hog gastric mucosa (1990), Jpn. J. Pharmacol., 52, 295-305.
    View publication on PubMed
Search for more literature for 7.2.2.19

Inhibitors

Inhibitors Comment Organism Structure
(CH3)4N+
-
 Sus scrofa
Ba2+
-
 Sus scrofa
Ca2+
-
 Sus scrofa
Cd2+
-
 Sus scrofa
Cu2+
-
 Sus scrofa
Li+
-
 Sus scrofa
N,N'-dicyclohexylcarbodiimide
-
 Sus scrofa
Na+
-
 Sus scrofa
Omeprazole pH-dependent inhibition Sus scrofa
p-chloromercuribenzene sulfonate
-
 Sus scrofa
Sr2+
-
 Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Sus scrofa 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
K+ stimulates , maximal activity at 5 mM Sus scrofa
NH4+ stimulates, maximal activity at 20 mM Sus scrofa
Rb+ stimulates Sus scrofa
Tl+ stimulates Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
 hog
-

Purification (Commentary)

Purification (Comment) Organism
-
 Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
stomach gastric mucosa Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-deoxyATP + H2O + H+/in + K+/out 37% of the activity with ATP Sus scrofa 2'-deoxyADP + phosphate + H+/out + K+/in
-
 ?
ADP + H2O + H+/in + K+/out 7.5% of the activity with ATP Sus scrofa AMP + phosphate + H+/out + K+/in
-
 ?
ATP + H2O + H+/in + K+/out
-
 Sus scrofa ADP + phosphate + H+/out + K+/in
-
 ?
CTP + H2O + H+/in + K+/out 13.2% of the activity with ATP Sus scrofa CDP + phosphate + H+/out + K+/in
-
 ?

Subunits

Subunits Comment Organism
?
-
 Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
-
 Sus scrofa

pH Range

pH Minimum pH Maximum Comment Organism
6.8 7.8 pH 6.8: about 60% of maximal activity, pH 7.8: about 45% of maximal activity Sus scrofa