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Literature summary for 7.2.2.16 extracted from

  • Mademidis, A.; Koster, W.
    Transport activity of FhuA, FhuC, FhuD, and FhuB derivates in a system free of polar effects, and stoichiometry of components involved in ferrichrome uptake (1998), Mol. Gen. Genet., 285, 156-165.
    View publication on PubMed
Search for more literature for 7.2.2.16

Cloned(Commentary)

Cloned (Comment) Organism
fhu cassette operon expressed in a chromosomal fhu deletion mutant Escherichia coli

Protein Variants

Protein Variants Comment Organism
G226A FhuB(N), negative effect on FhuB-mediated transport Escherichia coli
G226E FhuB(N), negative effect on FhuB-mediated transport Escherichia coli
G226V FhuB(N), negative effect on FhuB-mediated transport Escherichia coli
G559A FhuB(C), negative effect on FhuB-mediated transport Escherichia coli
G559E FhuB(C), negative effect on FhuB-mediated transport Escherichia coli
G559V FhuB(C), negative effect on FhuB-mediated transport Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasmic membrane ExbB Escherichia coli
-
-
cytoplasmic membrane FhuB, integral Escherichia coli
-
-
cytoplasmic membrane TonB Escherichia coli
-
-
cytoplasmic membrane ExbD Escherichia coli
-
-
periplasm FhuD, periplasmic binding Escherichia coli
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + iron(III) hydroxamates/out Escherichia coli
-
 ADP + phosphate + iron(III) hydroxamates/in
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + iron(III) hydroxamates/out
-
 Escherichia coli ADP + phosphate + iron(III) hydroxamates/in
-
 ?

Subunits

Subunits Comment Organism
More ATP-transporter Escherichia coli
More components involved are FhuA (receptor), TonB, ExbB, ExbD and FhuC, FhuD, FhuB Escherichia coli