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Literature summary for 7.2.2.13 extracted from

  • El Moussawi, L.; Chakkour, M.; Kreydiyyeh, S.I.
    Epinephrine modulates Na+/K+ ATPase activity in Caco-2 cells via Src, p38MAPK, ERK and PGE2 (2018), PLoS ONE, 13, e0193139 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.2.2.13

Inhibitors

Inhibitors Comment Organism Structure
epinephrine 0.5 mM epinephrine added for 20 min, decreases the activity of the enzyme by around 50%. Treatment with Rp-cAMP, indomethacin, PP2, SB202190, and PD98059 completely abrogate the effect of epinephrine Homo sapiens
Ouabain specific inhibitor Homo sapiens
prostaglandin E2
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + 3 Na+[side 1] + 2 K+[side 2] Homo sapiens
-
 ADP + phosphate + 3 Na+[side 2] + 2 K+[side 1]
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Caco-2 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + 3 Na+[side 1] + 2 K+[side 2]
-
 Homo sapiens ADP + phosphate + 3 Na+[side 2] + 2 K+[side 1]
-
 ?

Synonyms

Synonyms Comment Organism
Na+/K+ ATPase
-
 Homo sapiens