Literature summary for 7.2.2.13 extracted from

Fabri, L.M.; Lucena, M.N.; Garcon, D.P.; Moraes, C.M.; McNamara, J.C.; Leone, F.A.
Kinetic characterization of the gill (Na+, K+)-ATPase in a hololimnetic population of the diadromous Amazon River shrimp Macrobrachium amazonicum (Decapoda, Palaemonidae) (2019), Comp. Biochem. Physiol. B, 227, 64-74 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
Aurovertin	-	Macrobrachium amazonicum
bafilomycin	-	Macrobrachium amazonicum
DMSO	-	Macrobrachium amazonicum
EGTA	-	Macrobrachium amazonicum
Ethacrynic acid	-	Macrobrachium amazonicum
ethanol	-	Macrobrachium amazonicum
orthovanadate	-	Macrobrachium amazonicum
Ouabain	-	Macrobrachium amazonicum
thapsigargin	-	Macrobrachium amazonicum
theophylline	-	Macrobrachium amazonicum

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
microsome	-	Macrobrachium amazonicum	-	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	required in form of Mg-ATP	Macrobrachium amazonicum

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + Na+[side 1] + K+[side 2]	Macrobrachium amazonicum	-	ADP + phosphate + Na+[side 2] + K+[side 1]	-	?

Organism

Organism	UniProt	Comment	Textmining
Macrobrachium amazonicum	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
gill	-	Macrobrachium amazonicum	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + Na+[side 1] + K+[side 2]	-	Macrobrachium amazonicum	ADP + phosphate + Na+[side 2] + K+[side 1]	-	?

Subunits

Subunits	Comment	Organism
?	x * 110000, alpha subunit, SDS-PAGE	Macrobrachium amazonicum

Synonyms

Synonyms	Comment	Organism
(Na+, K+)-ATPase	-	Macrobrachium amazonicum

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.18	-	Ouabain	at pH 7.5 and 25°C	Macrobrachium amazonicum

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Release 2023.1 (January 2023)