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Literature summary for 7.2.2.13 extracted from

  • Roy, M.; Sivan-Loukianova, E.; Eberl, D.F.
    Cell-type-specific roles of Na+/K+ ATPase subunits in Drosophila auditory mechanosensation (2013), Proc. Natl. Acad. Sci. USA, 110, 181-186.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.2.2.13

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Na+/in + K+/out Drosophila melanogaster
-
 ADP + phosphate + Na+/out + K+/in
-
 ?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Johnston's organ
-
 Drosophila melanogaster
-
scolopale cell
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Na+/in + K+/out
-
 Drosophila melanogaster ADP + phosphate + Na+/out + K+/in
-
 ?

Synonyms

Synonyms Comment Organism
ATPalpha catalytic subunit Drosophila melanogaster
Na pump
-
 Drosophila melanogaster
Na+/K+-ATPase
-
 Drosophila melanogaster

General Information

General Information Comment Organism
malfunction knocking down of catalytic subunit ATPalpha, but not alpha-like, in the entire Johnston's organ results in complete deafness. Knocking down beta subunit nrv2 in scolopale cells reduces ATPalpha expression in scolopale cells and causes almost complete deafness Drosophila melanogaster
physiological function the catalytic subunit ATPalpha is required for hearing Drosophila melanogaster