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Literature summary for 7.2.2.13 extracted from

  • Galarza-Munoz, G.; Soto-Morales, S.I.; Holmgren, M.; Rosenthal, J.J.
    Physiological adaptation of an Antarctic Na+/K+-ATPase to the cold (2011), J. Exp. Biol., 214, 2164-2174.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Xenopus laevis Pareledone sp.
expression in Xenopus laevis Octopus bimaculatus

Organism

Organism UniProt Comment Textmining
Octopus bimaculatus F8V2T6 alpha-subunit
-
Pareledone sp. F8V2T5 alpha-subunit
-
Pareledone sp. GG-2011 F8V2T5 alpha-subunit
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 3 Na+/in
-
Pareledone sp. ADP + phosphate + 3 Na+/out
-
?
ATP + 3 Na+/in
-
Octopus bimaculatus ADP + phosphate + 3 Na+/out
-
?
ATP + 3 Na+/in
-
Pareledone sp. GG-2011 ADP + phosphate + 3 Na+/out
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
additional information
-
comparison of temperature sensitivity of the endogenous pump current of Na+/K+-ATPase in Antarctic Pareledone sp. and temperate Octopus bimaculatus. The voltage dependence of the pumps is equivalent. At room temperature the maximum turnover rate of the Antarctic pump is 25% higher than that of the temperate pump. In addition, the Antarctic pump exhibits a lower temperature sensitivity, leading to significantly higher relative activity at lower temperatures Pareledone sp.
additional information
-
comparison of temperature sensitivity of the endogenous pump current of Na+/K+-ATPase in Antarctic Pareledone sp. and temperate Octopus bimaculatus. The voltage dependence of the pumps is equivalent. At room temperature the maximum turnover rate of the Antarctic pump is 25% higher than that of the temperate pump. In addition, the Antarctic pump exhibits a lower temperature sensitivity, leading to significantly higher relative activity at lower temperatures Octopus bimaculatus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
20.1
-
Na+/in maximum turnover rate per pump, pH not specified in the publication, 22°C Octopus bimaculatus
25.5
-
Na+/in maximum turnover rate per pump, pH not specified in the publication, 22°C Pareledone sp.