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Literature summary for 7.2.2.13 extracted from

  • Garcon, D.P.; Masui, D.C.; Mantelatto, F.L.; McNamara, J.C.; Furriel, R.P.; Leone, F.A.
    K+ and NH+4 modulate gill (Na+,K+)-ATPase activity in the blue crab, Callinectes ornatus: Fine tuning of ammonia excretion (2007), Comp. Biochem. Physiol. A, 147A, 145-155.
    View publication on PubMed
Search for more literature for 7.2.2.13

Activating Compound

Activating Compound Comment Organism Structure
NH4+ stimulation, following a single saturation curve. Synergistic effects of K+ and NH4+. At elevated concentrations of NH4+, enzyme is fully active and K+ cannot displace NH4+ from its exclusive binding sites Callinectes ornatus

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibitory: NH4+. At elevated concentrations of NH4+, enzyme is fully active and K+ cannot displace NH4+ from its exclusive binding sites Callinectes ornatus
orthovanadate up to 87% inhibition Callinectes ornatus
Ouabain up to 87% inhibition Callinectes ornatus

Metals/Ions

Metals/Ions Comment Organism Structure
K+ stimulation, following a single saturation curve. Synergistic effects of K+ and NH4+ Callinectes ornatus
Mg2+ stimulation, following a single saturation curve Callinectes ornatus
Na+ stimulation, following a single saturation curve Callinectes ornatus

Organism

Organism UniProt Comment Textmining
Callinectes ornatus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
gill
-
 Callinectes ornatus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 3 Na+/in reaction obeys Michaelis-Menten kinetics Callinectes ornatus ADP + phosphate + 3 Na+/out
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