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Literature summary for 7.2.2.13 extracted from

  • Lee, S.Y.; Lee, C.O.
    Inhibition of Na+-K+ pump and L-type Ca2+ channel by glibenclamide in guinea pig ventricular myocytes (2005), J. Pharmacol. Exp. Ther., 312, 61-68.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
glibenclamide
-
Cavia porcellus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Cavia porcellus 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + phosphate + Na+/out Cavia porcellus
-
ATP + H2O + Na+/in
-
?
ATP + H2O + K+/in Cavia porcellus
-
ADP + phosphate + K+/out
-
?

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
myocyte ventricular myocyte Cavia porcellus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + phosphate + Na+/out
-
Cavia porcellus ATP + H2O + Na+/in
-
?
ATP + H2O + K+/in
-
Cavia porcellus ADP + phosphate + K+/out
-
?

Synonyms

Synonyms Comment Organism
Na+-K+ pump
-
Cavia porcellus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
myocytes in the experimental chamber for measurement of Na+-K+ pump current Cavia porcellus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
myocytes in the experimental chamber for measurement of Na+-K+ pump current Cavia porcellus