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Literature summary for 7.2.2.13 extracted from

  • Peluffo, R.D.
    Effect of ADP on Na(+)-Na(+) exchange reaction kinetics of Na,K-ATPase (2004), Biophys. J., 87, 883-898.
    View publication on PubMedView publication on EuropePMC

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + phosphate + Na+/out Rattus norvegicus each cycle extrudes 3 Na+ from the cell and moves 2 K+ into the cell with utilization of 1 ATP ATP + H2O + Na+/in
-
?
ATP + H2O + K+/in Rattus norvegicus
-
ADP + phosphate + K+/out
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cardiac myocyte
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + phosphate + 3 Na+/out in the absence of K+ and in the presence of ATP and ADP without net ATP hydrolysis Rattus norvegicus ATP + 3 Na+/in transphosphorylation of ATP/ADP ?
ADP + phosphate + Na+/out each cycle extrudes 3 Na+ from the cell and moves 2 K+ into the cell with utilization of 1 ATP Rattus norvegicus ATP + H2O + Na+/in
-
?
ATP + 3 Na+/in
-
Rattus norvegicus ADP + phosphate + 3 Na+/out
-
?
ATP + H2O + K+/in
-
Rattus norvegicus ADP + phosphate + K+/out
-
?

Synonyms

Synonyms Comment Organism
Na,K-ATPase
-
Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
23
-
myocytes in superfusion chamber Rattus norvegicus