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Literature summary for 7.2.2.12 extracted from

  • Chaoprasid, P.; Nookabkaew, S.; Sukchawalit, R.; Mongkolsuk, S.
    Roles of Agrobacterium tumefaciens C58 ZntA and ZntB and the transcriptional regulator ZntR in controlling Cd2+/Zn2+/Co2+ resistance and the peroxide stress response (2015), Microbiology, 161, 1730-1740.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Agrobacterium tumefaciens
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Agrobacterium tumefaciens C58 / ATCC 33970
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Synonyms

Synonyms Comment Organism
ZntA
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Agrobacterium tumefaciens

Expression

Organism Comment Expression
Agrobacterium tumefaciens expression of the zntA gene is inducible by CdCl2, ZnCl2 and CoCl2, of which CdCl2 is the most potent inducer. The metal-induced expression of zntA is controlled by the MerR-like regulator ZntR up

General Information

General Information Comment Organism
physiological function transporter zntA and regulator zntR mutants are highly sensitive to CdCl2 and ZnCl2, and to a lesser extent to CoCl2. The inactivation of zntA increases the accumulation of intracellular cadmium and zinc, and confers hyperresistance to H2O2. The loss of either the zntA or zntR gene does not affect the virulence of Agrobacterium tumefaciens in Nicotiana benthamiana Agrobacterium tumefaciens