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Literature summary for 7.2.2.12 extracted from

  • Dutta, S.J.; Liu, J.; Hou, Z.; Mitra, B.
    Conserved aspartic acid 714 in transmembrane segment 8 of the ZntA Subgroup of P1B-type ATPases is as metal-binding residue (2006), Biochemistry, 45, 5923-5931.
    View publication on PubMed
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Protein Variants

Protein Variants Comment Organism
D714A mutant enzyme is not able to confer resistance to Pb2+, Zn2+, and Cd2+ salts, large reduction in ATPase activity Escherichia coli
D714E mutant enzyme is not able to confer resistance to Pb2+, Zn2+, and Cd2+ salts, large reduction in ATPase activity, retains the ability to bind metal ions with high affinity at the transmembrane site Escherichia coli
D714H mutant enzyme is not able to confer resistance to Pb2+, Zn2+, and Cd2+ salts, large reduction in ATPase activity, retains the ability to bind metal ions with high affinity at the transmembrane site Escherichia coli
D714P mutant enzyme is not able to confer resistance to Pb2+, Zn2+, and Cd2+ salts, large reduction in ATPase activity Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining

Metals/Ions

Metals/Ions Comment Organism Structure
additional information conserved aspartic acid 714 in transmembrane segment 8 of the ZntA Subgroup of P1B-type ATPases is as metal-binding residue Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Synonyms

Synonyms Comment Organism
ZntA
-
 Escherichia coli