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Literature summary for 7.2.2.10 extracted from

  • Groten, C.J.; Rebane, J.T.; Hodgson, H.M.; Chauhan, A.K.; Blohm, G.; Magoski, N.S.
    Ca2+ removal by the plasma membrane Ca2+-ATPase influences the contribution of mitochondria to activity-dependent Ca2+ dynamics in Aplysia neuroendocrine cells (2016), J. Neurophysiol., 115, 2615-2634 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.2.2.10

Inhibitors

Inhibitors Comment Organism Structure
Ca2+
-
 Aplysia californica
carboxyeosin
-
 Aplysia californica
DMSO
-
 Aplysia californica
EGTA
-
 Aplysia californica

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Aplysia californica 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ required Aplysia californica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Ca2+[side 1] Aplysia californica
-
 ADP + phosphate + Ca2+[side 2]
-
 ?

Organism

Organism UniProt Comment Textmining
Aplysia californica
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bag cell neuron
-
 Aplysia californica
-
neuroendocrine cell
-
 Aplysia californica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Ca2+[side 1]
-
 Aplysia californica ADP + phosphate + Ca2+[side 2]
-
 ?

Synonyms

Synonyms Comment Organism
plasma membrane Ca2+-ATPase
-
 Aplysia californica
PMCA
-
 Aplysia californica

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00005
-
 Ca2+ pH and temperature not specified in the publication Aplysia californica

General Information

General Information Comment Organism
metabolism Ca2+ removal by the enzyme influences the propensity for stimulus-evoked Ca2+-induced Ca2+ release by adjusting the amount of Ca2+ available for mitochondrial Ca2+ uptake Aplysia californica