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Literature summary for 7.2.2.10 extracted from
- Mn2+ transport by Ca2+-ATPase of sarcoplasmic reticulum (2016), FEBS Lett., 590, 2086-2095 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| thapsigargin | - |
Oryctolagus cuniculus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| sarcoplasmic reticulum | - |
Oryctolagus cuniculus | 16529 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + Ca2+[side 1] | Oryctolagus cuniculus | - |
ADP + phosphate + Ca2+[side 2] | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | P04191 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| muscle | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + Ca2+[side 1] | - |
Oryctolagus cuniculus | ADP + phosphate + Ca2+[side 2] | - |
? | |
| ATP + H2O + Mn2+[side 1] | the enzyme has a much lower affinity for Mn2+ than for Ca2+ | Oryctolagus cuniculus | ADP + phosphate + Mn2+[side 2] | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Ca2+-ATPase | - |
Oryctolagus cuniculus |
| SERCA1a | - |
Oryctolagus cuniculus |
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Release 2023.1 (January 2023)
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