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Literature summary for 7.2.2.10 extracted from

  • Kosa, M.; Brinyiczki, K.; van Damme, P.; Goemans, N.; Hancsak, K.; Mendler, L.; Zador, E.
    The neonatal sarcoplasmic reticulum Ca2+-ATPase gives a clue to development and pathology in human muscles (2015), J. Muscle Res. Cell Motil., 36, 195-203.
    View publication on PubMed
Search for more literature for 7.2.2.10

Inhibitors

Inhibitors Comment Organism Structure
sarcolipin
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
sarcoplasmic reticulum
-
 Homo sapiens 16529
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Ca2+[side 1] Homo sapiens
-
 ADP + phosphate + Ca2+[side 2]
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
muscle isoform SERCA1b is only expressed in prematured infant leg and arm muscles. It is replaced by isoform SERCA1a in more matured neonatal muscles and is completely absent in human foetal and neonatal diaphragm. Only isoform SERCA1a and not SERCA1is detected in muscles of 7-12 years old boys with Duchenne. In adult patients with myotonic dystrophy type 2 the SERCA1b isoform dominates over SERCA1a Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Ca2+[side 1]
-
 Homo sapiens ADP + phosphate + Ca2+[side 2]
-
 ?

Synonyms

Synonyms Comment Organism
sarcoplasmic reticulum Ca2+-ATPase
-
 Homo sapiens
SERCA1b
-
 Homo sapiens