Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
Mus musculus | 5886 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
128000 | - |
x * 128000, splice variant PMCA4a, SDS-PAGE | Mus musculus |
133000 | - |
x * 133000, splice variant PMCA4b, SDS-PAGE | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Ca2+[side 1] | Mus musculus | - |
ADP + phosphate + Ca2+[side 2] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q6Q477 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epididymal fluid | - |
Mus musculus | - |
epididymis | apical membrane of the epididymal epithelium | Mus musculus | - |
testis | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Ca2+[side 1] | - |
Mus musculus | ADP + phosphate + Ca2+[side 2] | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 128000, splice variant PMCA4a, SDS-PAGE | Mus musculus |
? | x * 133000, splice variant PMCA4b, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
plasma membrane Ca2+-ATPase isoform 4 | - |
Mus musculus |
PMCA4a | splice variant | Mus musculus |
PMCA4b | splice variant | Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | the combination of the functional attributes of both PMCA4 variants leads to heightened efficiency of the pump in the maintenance of Ca2+ homeostasis, which is crucial for normal motility and male fertility | Mus musculus |