Literature summary for 7.2.2.10 extracted from

Naik, P.K.; Srivastava, M.; Bajaj, P.; Jain, S.; Dubey, A.; Ranjan, P.; Kumar, R.; Singh, H.
The binding modes and binding affinities of artemisinin derivatives with Plasmodium falciparum Ca2+-ATPase (PfATP6) (2011), J. Mol. Model., 17, 333-357.

Inhibitors

Inhibitors	Comment	Organism
(12S,12aR)-3-methyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(1R,9aR)-9-[2-[(4-fluorobenzyl)oxy]ethyl]-1-methoxy-3-methyloctahydro-3,9a-epidioxy-2-benzoxepine	-	Plasmodium falciparum
(1S,6R,9aS)-3,6-dimethyloctahydro-3,9a-epidioxy-2-benzoxepin-1(1H)-yl phenylacetate	-	Plasmodium falciparum
(1S,9aR)-1-methoxy-3-methyl-9-[2-(phenylperoxy)ethyl]octahydro-3,9a-epidioxy-2-benzoxepine	-	Plasmodium falciparum
(1S,9aR)-1-methoxy-3-methyl-9-[2-(prop-2-en-1-yloxy)ethyl]octahydro-3,9a-epidioxy-2-benzoxepine	-	Plasmodium falciparum
(1S,9aR)-9-[2-(benzyloxy)ethyl]-1-methoxy-3-methyloctahydro-3,9a-epidioxy-2-benzoxepine	-	Plasmodium falciparum
(1S,9aS)-1-methoxy-3-methyloctahydro-3,9a-epidioxy-2-benzoxepine	-	Plasmodium falciparum
(1S,9aS)-1-[2-(benzyloxy)ethyl]-1,3,9-trimethyloctahydro-3,9a-epidioxy-2-benzoxepine	-	Plasmodium falciparum
(3R,5aS,6R,8aS,12aS)-11-benzyl-3,6-dimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,12aS)-3,6-dimethyl-11-(2-methylbutyl)decahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,12aS)-3,6-dimethyl-11-(2-phenylethyl)decahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,12aS)-3,6-dimethyl-11-(3-phenylpropyl)decahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,12aS)-3,6-dimethyl-11-(4-methylbenzyl)decahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,12aS)-3,6-dimethyl-11-pentyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,12aS)-3-butyl-6-methyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,12aS)-3-ethyl-6-methyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,12aS)-3-[3-(4-chlorophenyl)propyl]-6-methyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,12aS)-6-methyl-3-(3-phenylpropyl)octahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,12aS)-6-methyl-3-propyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,9R,12aR)-3,9-dibutyl-6-methyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,9R,12aR)-9-butyl-3-ethyl-6-methyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,9R,12aR)-9-butyl-3-[3-(4-chlorophenyl)propyl]-6-methyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,9R,12aR)-9-butyl-6-methyl-3-(4-phenylbutyl)octahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(3R,5aS,6R,8aS,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol	-	Plasmodium falciparum
(3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(3R,6R,9R,12R,12aR)-6,9-dimethyl-10-(2,2,2-trifluoroethyl)decahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-9-ol	-	Plasmodium falciparum
(3R,6R,9S,12R,12aR)-10-ethoxy-6,9-dimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-9-ol	-	Plasmodium falciparum
(3R,6R,9S,12R,12aR)-6,9-dimethyl-10-(2,2,2-trifluoroethyl)decahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-9-ol	-	Plasmodium falciparum
(3R,6R,9S,12R,12aR)-6,9-dimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene-9,10-diol	-	Plasmodium falciparum
(3S,5aR,6S,8aR,9R,12S,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl N-[(2-methylpropoxy)carbonyl]-b-alaninate	-	Plasmodium falciparum
(3S,5aS,6R,8aS,12aS)-6-methyl-3-(2-methylpropyl)octahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(3S,5aS,6R,8aS,12aS)-6-methyl-3-(2-phenylethyl)octahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(3S,5aS,6R,8aS,9R,12aR)-9-butyl-6-methyl-3-(2-phenylethyl)octahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(3S,6R,12R,12aS)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(4aS)-3,3-diethylhexahydro-6H-[1,2,4]trioxino[6,5-j]isochromen-6-one	-	Plasmodium falciparum
(4aS)-3,3-dimethylhexahydro-6H-[1,2,4]trioxino[6,5-j]isochromen-6-one	-	Plasmodium falciparum
(4aS)-hexahydro-6H-[1,2,4]trioxino[6,5-j]isochromen-6-one	-	Plasmodium falciparum
(5S,6R,9R,10S,12R,12aS)-10-ethoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-5-ol	-	Plasmodium falciparum
(6'R,12'S,12a'R)-3',6'-dimethyl-3',4',5',5a',6',7',8',8a'-octahydrospiro[cyclopent-3-ene-1,9'-[1,2,11,13]tetraoxa[3,12]epoxy[1,2]dioxepino[4,3-i]isochromen]-10'-one	-	Plasmodium falciparum
(6'R,12'S,12a'R)-3',6'-dimethyloctahydrospiro[1,3-dioxolane-2,9'-[3,12]epoxy[1,2]dioxepino[4,3-i]isochromen]-10'-one	-	Plasmodium falciparum
(6R,10R,12R,12aR)-3,6-dimethyl-9-methylidenedecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl hydroperoxide	-	Plasmodium falciparum
(6R,10R,12R,12aR)-3,6-dimethyloctahydrospiro[3,12-epoxy[1,2]dioxepino[4,3-i]isochromene-9,2'-oxiran]-10-ol	-	Plasmodium falciparum
(6R,10R,12R,12aR)-3,6-dimethyloctahydrospiro[3,12-epoxy[1,2]dioxepino[4,3-i]isochromene-9,2'-oxiran]-10-yl hydroperoxide	-	Plasmodium falciparum
(6R,10S,12R,12aR)-3,6-dimethyl-9-methylidenedecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol	-	Plasmodium falciparum
(6R,12aS)-11-(4-chlorobenzyl)-3,6-dimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(6R,12aS)-11-acetyl-3,6-dimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(6R,12aS)-11-benzyl-3,6-dimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(6R,12aS)-3,6-dimethyl-11-(2-phenylethyl)decahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(6R,12aS)-3,6-dimethyl-11-(3-phenylpropyl)decahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(6R,12aS)-3,6-dimethyl-11-(pyridin-2-ylmethyl)decahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(6R,12aS)-3,6-dimethyl-11-(thiophen-2-yl)decahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(6R,12aS)-3,6-dimethyl-11-pentyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-10(3H)-one	-	Plasmodium falciparum
(6R,12R,12aR)-3,6-dimethyl-9-methylidenedecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl hydroperoxide	-	Plasmodium falciparum
(6R,12R,12aS)-3-butyl-6-methyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,12R,12aS)-3-ethyl-6-methyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,12R,12aS)-3-[3-(4-chlorophenyl)propyl]-6-methyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,12R,12aS)-6-methyl-3-(2-methylpropyl)decahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,12R,12aS)-6-methyl-3-(4-phenylbutyl)decahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,12R,12aS)-6-methyl-3-propyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,12S,12aS)-3,6-dimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,12S,12aS)-3-ethyl-6-methyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,12S,12aS)-6-methyl-3-(4-phenylbutyl)octahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,12S,12aS)-6-methyl-3-propyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,8aR,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,8aR,9R,12aR)-3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,8aR,9R,12S,12aR)-9-bromo-9-(bromomethyl)-3,6-dimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,8aS,9S,10R,12R,12aR)-3,6-dimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene-9,10-diol	-	Plasmodium falciparum
(6R,8aS,9Z,12S,12aR)-9-ethylidene-3,6-dimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9aS)-3,6-dimethyloctahydro-3,9a-epidioxy-2-benzoxepine	-	Plasmodium falciparum
(6R,9R,12R,12aR)-10-(tert-butylperoxy)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,9R,12R,12aR)-10-ethoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,9R,12R,12aR)-10-ethoxy-3,6-dimethyl-9-propyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,9R,12R,12aR)-10-ethoxy-9-ethyl-3,6-dimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,9R,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol	-	Plasmodium falciparum
(6R,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,9R,12R,12aR)-3,6-dimethyl-9-(3-phenylpropyl)decahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,9R,12R,12aR)-3,6-dimethyl-9-pentyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,9R,12R,12aR)-3,6-dimethyl-9-propyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,9R,12R,12aR)-3,6-dimethyloctahydrospiro[3,12-epoxy[1,2]dioxepino[4,3-i]isochromene-9,2'-oxiran]-10-yl hydroperoxide	-	Plasmodium falciparum
(6R,9R,12R,12aR)-9-butyl-3,6-dimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,9R,12R,12aR)-9-ethyl-3,6-dimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9R,12S,12aR)-3,6-dimethyl-3,4,4',5,5',5a,6,7,8,8a-decahydrospiro[3,12-epoxy[1,2]dioxepino[4,3-i]isochromene-9,3'-pyrazol]-10-one	-	Plasmodium falciparum
(6R,9R,12S,12aR)-3,6-dimethyl-9-(2-methylpropyl)octahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9R,12S,12aR)-3,6-dimethyl-9-(2-phenylethyl)octahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9R,12S,12aR)-3,6-dimethyl-9-(3-phenylpropyl)octahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9R,12S,12aR)-3,6-dimethyl-9-(4-phenylbutyl)octahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9R,12S,12aR)-3,6-dimethyl-9-(prop-2-en-1-yl)octahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9R,12S,12aR)-3,6-dimethyl-9-(propan-2-yl)octahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9R,12S,12aR)-3,6-dimethyl-9-pentyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9R,12S,12aR)-9-butyl-3,6-dimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9R,12S,12aR)-9-butyl-6-methyl-3-(4-phenylbutyl)octahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9R,12S,12aR)-9-ethyl-3,6-dimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9R,12S,12aR)-9-hexyl-3,6-dimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9R,12S,12aR)-9-[3-(4-chlorophenyl)propyl]-3,6-dimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9S,10R,12R,12aR)-3,6-dimethyloctahydrospiro[3,12-epoxy[1,2]dioxepino[4,3-i]isochromene-9,2'-oxiran]-10-yl hydroperoxide	-	Plasmodium falciparum
(6R,9S,11aR)-3,6,9-trimethyloctahydro-3H-3,11-epoxyfuro[3,4-j][1,2]benzodioxepine	-	Plasmodium falciparum
(6R,9S,12R,12aR)-9-bromo-3,6,9-trimethyl-N-phenyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-amine	-	Plasmodium falciparum
(6R,9S,12R,12aR)-9-bromo-3,6-dimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6R,9S,12S,12aR)-9-[(1E)-but-1-en-1-yl]-3,6-dimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6R,9S,12S,12aR)-9-[(2E)-but-2-en-1-yl]-3,6-dimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one	-	Plasmodium falciparum
(6S,7S,10S,12aS)-10-ethoxy-7-fluoro-3,6,7-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(6S,7S,10S,12R,12aS)-10-ethoxy-3,6-dimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-7-ol	-	Plasmodium falciparum
(6S,9R,10S,12aS)-10-ethoxy-3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-7(3H)-one	-	Plasmodium falciparum
(6S,9R,10S,12aS)-10-ethoxy-7,7-difluoro-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene	-	Plasmodium falciparum
(7R,12aR)-7,10-dimethyldodecahydro-2H-10,13-epoxy[1,2]dioxepino[4,3-i]pyrano[2,3-c]isochromene	-	Plasmodium falciparum
1,5-bis(4-methoxyphenyl)-6,7-dioxabicyclo[3.2.2]nonane	-	Plasmodium falciparum
1,5-diphenyl-3,6,7-trioxabicyclo[3.2.2]nonane	-	Plasmodium falciparum
1-[(6R)-3,3,6-trimethyloctahydro-9aH-1,2-benzodioxepin-9a-yl]ethanone	-	Plasmodium falciparum
2-(dimethylamino)ethyl 4-(2-oxo-2-[[(3S,5aR,6S,8aR,9R,12S,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy]ethyl)benzoate	-	Plasmodium falciparum
2-(dimethylamino)ethyl 4-[([2-[(1S,9aR)-1-methoxy-3-methyloctahydro-3,9a-epidioxy-2-benzoxepin-9(1H)-yl]ethyl]peroxy)methyl]benzoate	-	Plasmodium falciparum
2-[(1R,9aR)-1-methoxy-3-methyloctahydro-3,9a-epidioxy-2-benzoxepin-9(1H)-yl]ethyl diethylcarbamate	-	Plasmodium falciparum
2-[(1R,9aR)-1-methoxy-3-methyloctahydro-3,9a-epidioxy-2-benzoxepin-9(1H)-yl]ethyl diphenylcarbamate	-	Plasmodium falciparum
2-[(1S,9aS)-1,3,9-trimethyloctahydro-3,9a-epidioxy-2-benzoxepin-1(1H)-yl]ethanol	-	Plasmodium falciparum
2-[(1S,9aS)-1,3-dimethyloctahydro-3,9a-epidioxy-2-benzoxepin-1(1H)-yl]ethanol	-	Plasmodium falciparum
2-[(1S,9aS)-3,9-dimethyloctahydro-3,9a-epidioxy-2-benzoxepin-1(1H)-yl]ethanol	-	Plasmodium falciparum
3-[(6R,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]propan-1-ol	-	Plasmodium falciparum
4-(2-[2-[(1S,9aR)-1-methoxy-3-methyloctahydro-3,9a-epidioxy-2-benzoxepin-9(1H)-yl]ethoxy]ethyl)pyridine	-	Plasmodium falciparum
4-([2-[(1R,9aR)-1-methoxy-3-methyloctahydro-3,9a-epidioxy-2-benzoxepin-9(1H)-yl]ethoxy]methyl)pyrimidine	-	Plasmodium falciparum
4-([[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy]methyl)benzoic acid	-	Plasmodium falciparum
6-[(3R,5aS,6R,8aS,12aS)-3,6-dimethyl-10-oxodecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isoquinolin-11(12H)-yl]hexanoic acid	-	Plasmodium falciparum
artemisinin	-	Plasmodium falciparum
ethyl 3-[(3S,5aS,6R,8aS,12aS)-6-methyl-10-oxooctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-3(4H)-yl]propanoate	-	Plasmodium falciparum
ethyl 3-[(3S,5aS,6R,8aS,9R,12aR)-9-butyl-6-methyl-10-oxooctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-3(4H)-yl]propanoate	-	Plasmodium falciparum
ethyl 3-[(6R,12R,12aS)-6-methyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-3(4H)-yl]propanoate	-	Plasmodium falciparum
ethyl 3-[(6R,12S,12aS)-6-methyl-10-oxooctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-3(4H)-yl]propanoate	-	Plasmodium falciparum
ethyl 3-[(6R,9R,12S,12aR)-9-butyl-6-methyl-10-oxooctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-3(4H)-yl]propanoate	-	Plasmodium falciparum
ethyl [[(6R,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy]acetate	-	Plasmodium falciparum
methyl 2-methyl-3-[[(3R,5aS,6R,8aS,9R,10R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy]propanoate	-	Plasmodium falciparum
methyl 2-methyl-3-[[(6R,9R,10R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy]propanoate	-	Plasmodium falciparum
methyl 2-methyl-3-[[(6R,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy]propanoate	-	Plasmodium falciparum
methyl 2-[[(6R,9R,10R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy]propanoate	-	Plasmodium falciparum
methyl 2-[[(6R,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy]propanoate	-	Plasmodium falciparum
methyl 3-[[(3R,5aS,6R,8aS,9R,10R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy]butanoate	-	Plasmodium falciparum
methyl 3-[[(6R,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy]propanoate	-	Plasmodium falciparum
methyl 4-(2-oxo-2-[[(3S,5aR,6S,8aR,9R,12S,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy]ethyl)benzoate	-	Plasmodium falciparum
methyl 4-([[(6R,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy]methyl)benzoate	-	Plasmodium falciparum
methyl 4-[[(6R,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy]butanoate	-	Plasmodium falciparum
N-[(6R,9R,12R,12aR)-9-bromo-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]pyridin-2-amine	-	Plasmodium falciparum
N-[(6R,9S,12R,12aR)-9-bromo-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]-1,3-thiazol-2-amine	-	Plasmodium falciparum
N-[(6R,9S,12R,12aR)-9-bromo-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]pyridin-2-amine	-	Plasmodium falciparum
tert-butyl [(1E)-1-([2-[(1S,9aR)-1-methoxy-3-methyloctahydro-3,9a-epidioxy-2-benzoxepin-9(1H)-yl]ethyl]peroxy)ethylidene]carbamate	-	Plasmodium falciparum
thapsigargin	highly specific inhibitor	Plasmodium falciparum
[3-[(6R,9R,12S,12aR)-9-butyl-6-methyl-10-oxooctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-3(4H)-yl]propyl]phenylphosphinous chloride	-	Plasmodium falciparum

Organism

Organism	UniProt	Comment	Textmining
Plasmodium falciparum	Q08853	-	-
Plasmodium falciparum W-2	Q08853	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + Ca2+/out	-	Plasmodium falciparum	ADP + phosphate + Ca2+/in	-	?
ATP + H2O + Ca2+/out	-	Plasmodium falciparum W-2	ADP + phosphate + Ca2+/in	-	?

Synonyms

Synonyms	Comment	Organism
ATP6	-	Plasmodium falciparum
Ca2+-ATPase	-	Plasmodium falciparum
sarco/endoplasmic reticulum Ca2+-ATPase	-	Plasmodium falciparum