Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 7.2.2.10 extracted from

  • Aureliano, M.; Henao, F.; Tiago, T.; Duarte, R.O.; Moura, J.J.; Baruah, B.; Crans, D.C.
    Sarcoplasmic reticulum calcium ATPase is inhibited by organic vanadium coordination compounds: pyridine-2,6-dicarboxylatodioxovanadium(V), BMOV, and an amavadine analogue (2008), Inorg. Chem., 47, 5677-5684.
    View publication on PubMed
Search for more literature for 7.2.2.10

Inhibitors

Inhibitors Comment Organism Structure
bis(maltolato)oxovanadium(IV)
-
 Oryctolagus cuniculus
bis(N-hydroxylamidoiminodiacetato)vanadium(IV)
-
 Oryctolagus cuniculus
pyridine-2,6-dicarboxylatodioxovanadium
-
 Oryctolagus cuniculus
vanadate
-
 Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
sarcoplasmic reticulum
-
 Oryctolagus cuniculus 16529
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
skeletal muscle
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Ca2+/cis
-
 Oryctolagus cuniculus ADP + phosphate + Ca2+/trans
-
 ?

Synonyms

Synonyms Comment Organism
sarcoplasmic reticulum calcium ATPase
-
 Oryctolagus cuniculus
SR Ca2+-ATPase
-
 Oryctolagus cuniculus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.025
-
 in 25 mM HEPES (pH 7.0), 100 mM KCl, 5 mM MgCl2, 0.05 mM CaCl2, at 25°C Oryctolagus cuniculus pyridine-2,6-dicarboxylatodioxovanadium
0.04
-
 in 25 mM HEPES (pH 7.0), 100 mM KCl, 5 mM MgCl2, 0.05 mM CaCl2, at 25°C Oryctolagus cuniculus bis(maltolato)oxovanadium(IV)
0.08
-
 in 25 mM HEPES (pH 7.0), 100 mM KCl, 5 mM MgCl2, 0.05 mM CaCl2, at 25°C Oryctolagus cuniculus vanadate
0.325
-
 in 25 mM HEPES (pH 7.0), 100 mM KCl, 5 mM MgCl2, 0.05 mM CaCl2, at 25°C Oryctolagus cuniculus bis(N-hydroxylamidoiminodiacetato)vanadium(IV)