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Literature summary for 7.2.2.10 extracted from

  • Bookchin, R.M.; Etzion, Z.; Lew, V.L.; Tiffert, T.
    Preserved function of the plasma membrane calcium pump of red blood cells from diabetic subjects with high levels of glycated haemoglobin (2009), Cell Calcium, 45, 260-263.
    View publication on PubMed
Search for more literature for 7.2.2.10

Inhibitors

Inhibitors Comment Organism Structure
additional information glycation of a lysine residue near the catalytic site of the pump ATPase has a powerful inhibitory effect, in intact cells the Ca2+ pump is protected from glycation-induced inactivation Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Homo sapiens 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the activity of the plasma membrane Ca2+-pump decreases steeply throughout the 120 days lifespan of normal human red blood cells, the Ca2+ pump is a major regulator of Ca2+ homeostasis in all cells ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Ca2+/cis
-
 Homo sapiens ADP + phosphate + Ca2+/trans
-
 ?
additional information the activity of the plasma membrane Ca2+-pump decreases steeply throughout the 120 days lifespan of normal human red blood cells, the Ca2+ pump is a major regulator of Ca2+ homeostasis in all cells Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
plasma membrane Ca2+-pump
-
 Homo sapiens