Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | isoform SERCA3f mRNA is up-regulated in failing hearts | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | isoform SERCA3f may account for the mechanism of endoplasmic reticulum stress in vivo in heart failure | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
additional information | uniform distribution of SERCA3a | Homo sapiens | - |
- |
nucleus | isoform SERCA3d is observed around the nucleus | Homo sapiens | 5634 | - |
plasma membrane | isoform SERCA3f is observed in close vicinity of plasma membrane | Homo sapiens | 5886 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | dependent on | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
109200 | - |
isoform SERCA3a, SDS-PAGE | Homo sapiens |
112600 | - |
isoform SERCA3f, SDS-PAGE | Homo sapiens |
114100 | - |
isoform SERCA3d, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cardiomyocyte | - |
Homo sapiens | - |
heart | - |
Homo sapiens | - |
HEK-293 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Ca2+/cis | - |
Homo sapiens | ADP + phosphate + Ca2+/trans | - |
? |
Synonyms | Comment | Organism |
---|---|---|
sarco/endoplasmic reticulum Ca2+ ATPase 3 | - |
Homo sapiens |
SERCA3a | isoform | Homo sapiens |
SERCA3b | isoform | Homo sapiens |
SERCA3c | isoform | Homo sapiens |
SERCA3d | isoform | Homo sapiens |
SERCA3f | isoform | Homo sapiens |