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Literature summary for 7.2.2.10 extracted from

  • Faddy, H.M.; Smart, C.E.; Xu, R.; Lee, G.Y.; Kenny, P.A.; Feng, M.; Rao, R.; Brown, M.A.; Bissell, M.J.; Roberts-Thomson, S.J.; Monteith, G.R.
    Localization of plasma membrane and secretory calcium pumps in the mammary gland (2008), Biochem. Biophys. Res. Commun., 369, 977-981.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
Mus musculus 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mammary gland SPCA2 is expressed predominately in luminal epithelial cells of the mouse mammary gland during lactation with noexpression in cells outside the acini, SPCA1 is found in all cell types of the tissue section including myoepithelial and stromal cells, PMCA2 expression appears confined to the alveolus, whereas non-acinar cells do not express PMCA2, PMCA1 is ubiquitously expressed in the mammary gland sections with expression outside the acini Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Ca2+/cis
-
Mus musculus ADP + phosphate + Ca2+/trans
-
?

Synonyms

Synonyms Comment Organism
plasma membrane calcium ATPase
-
Mus musculus
PMCA1 isoform Mus musculus
PMCA2 isoform Mus musculus
secretory pathway Ca2+-ATPase
-
Mus musculus
SPCA1 isoform Mus musculus
SPCA2 isoform Mus musculus