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Literature summary for 7.2.2.1 extracted from

  • Romero-Vasquez, F.; Chavez, M.; Perez, M.; Arcaya, J.; Garcia, A.; Rincon, J.; Rodriguez-Iturbe, B.
    Overexpression of HGF transgene attenuates renal inflammatory mediators, Na+-ATPase activity and hypertension in spontaneously hypertensive rats (2012), Biochim. Biophys. Acta, 1822, 1590-1599.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
Furosemide
-
 Rattus norvegicus
additional information not inhibited by ouabain Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Na+/in Rattus norvegicus
-
 ADP + phosphate + Na+/out
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Na+/in
-
 Rattus norvegicus ADP + phosphate + Na+/out
-
 ?

Synonyms

Synonyms Comment Organism
Na+-ATPase
-
 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus the activity of Na+-ATPase is increased in rats receiving weekly hydrodynamic injection (1 mg/kg) of a naked plasmid containing human HGF gene associated with a cytomegalovirus promoter during 6 weeks up