Inhibitors | Comment | Organism | Structure |
---|---|---|---|
destruxin B | peptidic antibiotic, inhibits the ATPase activity | Enterococcus hirae | |
additional information | not inhibited by amiloride, vanadate or azide | Enterococcus hirae | |
N,N'-dicyclohexylcarbodiimide | inhibits in a pH dependent manner, binding covalently to acidic amino acid residues, inactivation is prevented by the presence of Na+ and Li+ | Enterococcus hirae | |
N-ethylmaleimide | inhibition of ATPase activity | Enterococcus hirae | |
NO3- | inhibition of ATPase activity | Enterococcus hirae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.02 | - |
Na+/in | pH 8 | Enterococcus hirae | |
0.06 | - |
Li+/in | pH 8 | Enterococcus hirae | |
3.5 | - |
Li+/in | pH 8 | Enterococcus hirae | |
4 | - |
Na+/in | pH 8 | Enterococcus hirae |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
11000 | - |
3 * 66000 + 3 * 51000 + 1 * 38000 + 1 * 27000 + 3 * 23000 + 2 (or 3) * 14000 + 4 (or 6) * 11000 + 1 * 76000 + 2 (or 3) * 16000, SDS-PAGE | Enterococcus hirae |
14000 | - |
3 * 66000 + 3 * 51000 + 1 * 38000 + 1 * 27000 + 3 * 23000 + 2 (or 3) * 14000 + 4 (or 6) * 11000 + 1 * 76000 + 2 (or 3) * 16000, SDS-PAGE | Enterococcus hirae |
16000 | - |
3 * 66000 + 3 * 51000 + 1 * 38000 + 1 * 27000 + 3 * 23000 + 2 (or 3) * 14000 + 4 (or 6) * 11000 + 1 * 76000 + 2 (or 3) * 16000, SDS-PAGE | Enterococcus hirae |
23000 | - |
3 * 66000 + 3 * 51000 + 1 * 38000 + 1 * 27000 + 3 * 23000 + 2 (or 3) * 14000 + 4 (or 6) * 11000 + 1 * 76000 + 2 (or 3) * 16000, SDS-PAGE | Enterococcus hirae |
27000 | - |
3 * 66000 + 3 * 51000 + 1 * 38000 + 1 * 27000 + 3 * 23000 + 2 (or 3) * 14000 + 4 (or 6) * 11000 + 1 * 76000 + 2 (or 3) * 16000, SDS-PAGE | Enterococcus hirae |
38000 | - |
3 * 66000 + 3 * 51000 + 1 * 38000 + 1 * 27000 + 3 * 23000 + 2 (or 3) * 14000 + 4 (or 6) * 11000 + 1 * 76000 + 2 (or 3) * 16000, SDS-PAGE | Enterococcus hirae |
51000 | - |
3 * 66000 + 3 * 51000 + 1 * 38000 + 1 * 27000 + 3 * 23000 + 2 (or 3) * 14000 + 4 (or 6) * 11000 + 1 * 76000 + 2 (or 3) * 16000, SDS-PAGE | Enterococcus hirae |
66000 | - |
3 * 66000 + 3 * 51000 + 1 * 38000 + 1 * 27000 + 3 * 23000 + 2 (or 3) * 14000 + 4 (or 6) * 11000 + 1 * 76000 + 2 (or 3) * 16000, SDS-PAGE | Enterococcus hirae |
76000 | - |
3 * 66000 + 3 * 51000 + 1 * 38000 + 1 * 27000 + 3 * 23000 + 2 (or 3) * 14000 + 4 (or 6) * 11000 + 1 * 76000 + 2 (or 3) * 16000, SDS-PAGE | Enterococcus hirae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Enterococcus hirae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Li+/in | coupled to Li+ translocation across the cytoplasmic membrane | Enterococcus hirae | ADP + phosphate + Li+/out | - |
? | |
ATP + H2O + Na+/in | coupled to Na+ translocation across the cytoplasmic membrane | Enterococcus hirae | ADP + phosphate + Na+/out | - |
? |
Subunits | Comment | Organism |
---|---|---|
multimer | 3 * 66000 + 3 * 51000 + 1 * 38000 + 1 * 27000 + 3 * 23000 + 2 (or 3) * 14000 + 4 (or 6) * 11000 + 1 * 76000 + 2 (or 3) * 16000, SDS-PAGE | Enterococcus hirae |
Synonyms | Comment | Organism |
---|---|---|
Na+-translocating ATPase | - |
Enterococcus hirae |
V-ATPase | - |
Enterococcus hirae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | 9 | - |
Enterococcus hirae |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.03 | - |
destruxin B | - |
Enterococcus hirae | |
0.2 | - |
N-ethylmaleimide | - |
Enterococcus hirae | |
37 | - |
NO3- | - |
Enterococcus hirae |