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Literature summary for 7.2.1.2 extracted from

  • Schlegel, K.; Welte, C.; Deppenmeier, U.; Mueller, V.
    Electron transport during aceticlastic methanogenesis by Methanosarcina acetivorans involves a sodium-translocating Rnf complex (2012), FEBS J., 279, 4444-4452.
    View publication on PubMed
Search for more literature for 7.2.1.2

Activating Compound

Activating Compound Comment Organism Structure
valinomycin in combination with K+, Na+ transport is stimulated slightly Methanosarcina acetivorans

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Methanosarcina acetivorans 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
K+ KCl itself has no effect on Na+ transport, in combination with valinomycin Na+ transport is stimulated slightly Methanosarcina acetivorans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 reduced ferredoxin [iron-sulfur] cluster + NAD+ + H+ + Na+[side 1] Methanosarcina acetivorans
-
 2 oxidized ferredoxin [iron-sulfur] cluster + NADH + Na+[side 2]
-
 ?

Organism

Organism UniProt Comment Textmining
Methanosarcina acetivorans
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 reduced ferredoxin [iron-sulfur] cluster + NAD+ + H+ + Na+[side 1]
-
 Methanosarcina acetivorans 2 oxidized ferredoxin [iron-sulfur] cluster + NADH + Na+[side 2]
-
 ?
2 reduced ferredoxin [iron-sulfur] cluster + NAD+ + H+ + Na+[side 1] Na+ transport is directly linked to ferredoxin:NAD+ oxidoreductase activity and is electrogenic Methanosarcina acetivorans 2 oxidized ferredoxin [iron-sulfur] cluster + NADH + Na+[side 2]
-
 ?
additional information inside-out membrane vesicles of catalyze Na+ transport coupled to an electron transport catalyzed by theferredoxin:heterodisulfide oxidoreductase activity Methanosarcina acetivorans ?
-
 ?

Synonyms

Synonyms Comment Organism
ferredoxin:heterodisulfide oxidoreductase
-
 Methanosarcina acetivorans
Fno
-
 Methanosarcina acetivorans
Rnf complex
-
 Methanosarcina acetivorans
sodium motive ferredoxin:NAD+ oxidoreductase
-
 Methanosarcina acetivorans

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 assay at Methanosarcina acetivorans

Cofactor

Cofactor Comment Organism Structure
Ferredoxin
-
 Methanosarcina acetivorans
NAD+
-
 Methanosarcina acetivorans

General Information

General Information Comment Organism
metabolism methanogenesis from acetate by Methanosarcina acetivorans involves an anaerobic electron transport chain with ferredoxin as electron donor and heterodisulfide as electron acceptor. Proposed model of the aceticlastic pathway of methanogenesis in Methanosarcina acetivorans, overview Methanosarcina acetivorans
physiological function the Rnf complex is a multi-subunit membrane-bound electron transport protein complex that is assumed to couple ferredoxin-dependent NAD+ reduction in bacteria with the translocation of ions across the cytoplasmic membrane. The electron transport during aceticlastic methanogenesis by Methanosarcina acetivorans involves a sodium-translocating Rnf complex, overview Methanosarcina acetivorans