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Literature summary for 7.2.1.1 extracted from

  • Toulouse, C.; Claussen, B.; Muras, V.; Fritz, G.; Steuber, J.
    Strong pH dependence of coupling efficiency of the Na+ - translocating NADH quinone oxidoreductase (Na+-NQR) of Vibrio cholerae (2017), Biol. Chem., 398, 251-260 .
    View publication on PubMed
Search for more literature for 7.2.1.1

Metals/Ions

Metals/Ions Comment Organism Structure
Li+ in presence of Li+, transmembrane voltage is generally lower than in presence of Na+, and the pH profile of electron transfer activity does not reveal a pronounced maximum Vibrio cholerae serotype O1
Na+ in presence of Na+, transmembrane voltage is barely influenced by pH (6.5-8.5), while quinone reduction activity exhibits a maximum at pH 7.5-8.0 Vibrio cholerae serotype O1

Organism

Organism UniProt Comment Textmining
Vibrio cholerae serotype O1 Q9KPS1 and Q9KPS2 and P0C6E0 and Q9X4Q6 and Q9X4Q7 and Q9X4Q8 Q9KPS1: subunit NqrA, Q9KPS2: subunit NqrB, P0C6E0: subunit NqrC, Q9X4Q6: subunit NqrD, Q9X4Q7: subunit NqrE, Q9X4Q8: subunit NqrF. The enzyme consists of six subunits encoded by the NQR operon.
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Vibrio cholerae serotype O1 ATCC 39315 Q9KPS1 and Q9KPS2 and P0C6E0 and Q9X4Q6 and Q9X4Q7 and Q9X4Q8 Q9KPS1: subunit NqrA, Q9KPS2: subunit NqrB, P0C6E0: subunit NqrC, Q9X4Q6: subunit NqrD, Q9X4Q7: subunit NqrE, Q9X4Q8: subunit NqrF. The enzyme consists of six subunits encoded by the NQR operon.
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the coupling efficiency of NQR is influenced by the nature of the transported cation, and by the concentration of protons. Partial uncoupling of the NQR observed with Li+, or with Na+ at pH 7.5-8.0, may be caused by the backflow of the coupling cation through the channel in subunit NqrB Vibrio cholerae serotype O1 ?
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additional information the coupling efficiency of NQR is influenced by the nature of the transported cation, and by the concentration of protons. Partial uncoupling of the NQR observed with Li+, or with Na+ at pH 7.5-8.0, may be caused by the backflow of the coupling cation through the channel in subunit NqrB Vibrio cholerae serotype O1 ATCC 39315 ?
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