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Literature summary for 7.2.1.1 extracted from

  • Barquera, B.; Ramirez-Silva, L.; Morgan, J.E.; Nilges, M.J.
    A new flavin radical signal in the Na(+)-pumping NADH:quinone oxidoreductase from Vibrio cholerae. An EPR/electron nuclear double resonance investigation of the role of the covalently bound flavins in subunits B and C (2006), J. Biol. Chem., 281, 36482-36491.
    View publication on PubMed
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Protein Variants

Protein Variants Comment Organism
T225Y lacks FMN in subunit NqrC, is not able to carry out electron transfer from NADH to ubiquinone, but instead from NADH to ferricyanide Vibrio cholerae serotype O1
T236Y lacks FMN in subunit NqrB, is not able to carry out electron transfer from NADH to ubiquinone, but instead from NADH to ferricyanide Vibrio cholerae serotype O1

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Vibrio cholerae serotype O1 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
[2Fe-2S]
-
 Vibrio cholerae serotype O1

Organism

Organism UniProt Comment Textmining
Vibrio cholerae serotype O1
-
-
-

Purification (Commentary)

Purification (Comment) Organism
D-salt polyacrylamide 6000 gel filtration Vibrio cholerae serotype O1

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADH + ubiquinone-1
-
 Vibrio cholerae serotype O1 NAD+ + ubiquinol-1
-
 ?

Subunits

Subunits Comment Organism
hexamer
-
 Vibrio cholerae serotype O1

Synonyms

Synonyms Comment Organism
Na(+)-pumping NADH:quinone oxidoreductase
-
 Vibrio cholerae serotype O1
Na+-NQR
-
 Vibrio cholerae serotype O1

Cofactor

Cofactor Comment Organism Structure
FMN
-
 Vibrio cholerae serotype O1
NADH
-
 Vibrio cholerae serotype O1