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Literature summary for 7.2.1.1 extracted from

  • Türk, K.; Puhar, A.; Neese, F.; Bill, E.; Fritz, G.; Steuber, J.
    NADH oxidation by the Na+-translocating NADH:quinone oxidoreductase from Vibrio cholerae: functional role of the NqrF subunit (2004), J. Biol. Chem., 279, 21349-21355.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Iron
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Vibrio cholerae serotype O1

Organism

Organism UniProt Comment Textmining
Vibrio cholerae serotype O1 Q9KPS1 and Q9KPS2 and P0C6E0 and Q9X4Q6 and Q9X4Q7 and Q9X4Q8 Q9KPS1: subunit NqrA, Q9KPS2: subunit NqrB, P0C6E0: subunit NqrC, Q9X4Q6: subunit NqrD, Q9X4Q7: subunit NqrE, Q9X4Q8: subunit NqrF. The enzyme consists of six subunits encoded by the NQR operon.
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Vibrio cholerae serotype O1 ATCC 39315 Q9KPS1 and Q9KPS2 and P0C6E0 and Q9X4Q6 and Q9X4Q7 and Q9X4Q8 Q9KPS1: subunit NqrA, Q9KPS2: subunit NqrB, P0C6E0: subunit NqrC, Q9X4Q6: subunit NqrD, Q9X4Q7: subunit NqrE, Q9X4Q8: subunit NqrF. The enzyme consists of six subunits encoded by the NQR operon.
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Subunits

Subunits Comment Organism
hexamer the NqrF subunit harbors the active site of NADH oxidation and acts as a converter between the hydride donor NADH and subsequent one-electron reaction steps in the Na+-translocating NADH:quinone oxidoreductase complex Vibrio cholerae serotype O1

Synonyms

Synonyms Comment Organism
Na+-NQR
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Vibrio cholerae serotype O1
Na+-translocating NADH:quinone oxidoreductase
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Vibrio cholerae serotype O1

Cofactor

Cofactor Comment Organism Structure
FAD the electron transfer NADH -> FAD ->[2Fe-2S] in NqrF requires positioning of the FAD and the Fe-S cluster in close proximity in accordance with a structural model of the subunit Vibrio cholerae serotype O1
NADH
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Vibrio cholerae serotype O1