Literature summary for 7.1.3.1 extracted from

Lin, I.; Knight, W.B.; Hsueh, A.; Dunaway-Mariano, D.
Investigation of the regiospecificity and stereospecificity of proton transfer in the yeast inorganic pyrophosphatase catalyzed reaction (1986), Biochemistry, 25, 4688-4692 .

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KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.3	-	Mg(H2O)4-thiodiphosphate	at pH 6.5 and 25°C	Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
diphosphate + H2O + H+[side 1]	Saccharomyces cerevisiae	-	2 phosphate + H+[side 2]	-	?

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Co(NH3)4-thiodiphosphate + H2O + H+[side 1]	-	Saccharomyces cerevisiae	?	-	?
Cr(H2O)4-thiodiphosphate + H2O + H+[side 1]	-	Saccharomyces cerevisiae	?	-	?
diphosphate + H2O + H+[side 1]	-	Saccharomyces cerevisiae	2 phosphate + H+[side 2]	-	?
Mg(H2O)4-diphosphate + H2O + H+[side 1]	-	Saccharomyces cerevisiae	?	-	?
Mg(H2O)4-thiodiphosphate + H2O + H+[side 1]	17% activity compared to Mg(H2O)4-diphosphate	Saccharomyces cerevisiae	?	-	?
additional information	the enzyme is unable to catalyze the hydrolysis of Mg(H2O)4-imidodiphosphate and Co(NH3)4-imidodiphosphate	Saccharomyces cerevisiae	?	-	?

Synonyms

Synonyms	Comment	Organism
inorganic pyrophosphatase	-	Saccharomyces cerevisiae
PPase	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)