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Literature summary for 7.1.3.1 extracted from

  • Soares Medeiros, L.C.; Moreira, B.L.; Miranda, K.; de Souza, W.; Plattner, H.; Hentschel, J.; Barrabin, H.
    A proton pumping pyrophosphatase in acidocalcisomes of Herpetomonas sp. (2005), Mol. Biochem. Parasitol., 140, 175-182.
    View publication on PubMed
Search for more literature for 7.1.3.1

Inhibitors

Inhibitors Comment Organism Structure
F-
-
 Herpetomonas sp.
Imidodiphosphate
-
 Herpetomonas sp.
Na+ inhibits diphosphate-dependent H+-uptake Herpetomonas sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
acidocalcisome acidic vacuole Herpetomonas sp. 20022
-
additional information subcellular localization, overview Herpetomonas sp.
-
-
vacuole acidic Herpetomonas sp. 5773
-

Metals/Ions

Metals/Ions Comment Organism Structure
K+ required for diphosphate-dependent H+-uptake Herpetomonas sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
diphosphate + H2O + H+[side 1] Herpetomonas sp.
-
 2 phosphate + H+[side 2]
-
 ?
additional information Herpetomonas sp. the enzyme acts as diphosphate-dependent H+-translocation pump, the organism regulates the intracellular distribution of H+ and Ca2+ in the plant host cell, mechanism ?
-
 ?

Organism

Organism UniProt Comment Textmining
Herpetomonas sp.
-
 plant parasite
-

Source Tissue

Source Tissue Comment Organism Textmining
promastigote
-
 Herpetomonas sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diphosphate + H2O + H+[side 1]
-
 Herpetomonas sp. 2 phosphate + H+[side 2]
-
 ?
additional information the enzyme acts as diphosphate-dependent H+-translocation pump, the organism regulates the intracellular distribution of H+ and Ca2+ in the plant host cell, mechanism Herpetomonas sp. ?
-
 ?
additional information the enzyme acts as diphosphate-dependent H+-translocation pump dependent on K+ in acidic vacuoles Herpetomonas sp. ?
-
 ?

Synonyms

Synonyms Comment Organism
proton pumping pyrophosphatase
-
 Herpetomonas sp.
V-H+-PPase
-
 Herpetomonas sp.

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Herpetomonas sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5 6.7
-
 Herpetomonas sp.

pH Range

pH Minimum pH Maximum Comment Organism
6 7.2 drastic loss of activity above pH 7.2 Herpetomonas sp.