Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | F1 strongly binds ADP lapsing into ADP inhibition, which pauses the rotation | Bacillus sp. (in: Bacteria) |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | molecular basis of positive cooperativity among three catalytic sites, acceleration of the ATP docking process occurs via thermally agitated conformational fluctuations, overview. Rate constants of ATP binding and hydrolysis are determined as functions of the rotary angle | Bacillus sp. (in: Bacteria) |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + H+/in | Bacillus sp. (in: Bacteria) | - |
ADP + phosphate + H+/out | - |
? | |
ATP + H2O + H+/in | Bacillus sp. (in: Bacteria) PS3 | - |
ADP + phosphate + H+/out | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus sp. (in: Bacteria) | - |
- |
- |
Bacillus sp. (in: Bacteria) PS3 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + H+/in | - |
Bacillus sp. (in: Bacteria) | ADP + phosphate + H+/out | - |
? | |
ATP + H2O + H+/in | the rate enhancement induced by ATP binding upon rotation is greater than that brought about by hydrolysis, suggesting that the ATP binding step contributes more to torque generation than does the hydrolysis step | Bacillus sp. (in: Bacteria) | ADP + phosphate + H+/out | - |
? | |
ATP + H2O + H+/in | - |
Bacillus sp. (in: Bacteria) PS3 | ADP + phosphate + H+/out | - |
? | |
ATP + H2O + H+/in | the rate enhancement induced by ATP binding upon rotation is greater than that brought about by hydrolysis, suggesting that the ATP binding step contributes more to torque generation than does the hydrolysis step | Bacillus sp. (in: Bacteria) PS3 | ADP + phosphate + H+/out | - |
? | |
GTP + H2O + H+/in | 3.3fold slower reaction compared to ATP hydrolysis | Bacillus sp. (in: Bacteria) | GDP + phosphate + H+/out | - |
? | |
GTP + H2O + H+/in | 3.3fold slower reaction compared to ATP hydrolysis | Bacillus sp. (in: Bacteria) PS3 | GDP + phosphate + H+/out | - |
? | |
additional information | angle dependence of ATP or GTP binding and of hydrolysis, overview. Modulation of the high reversibility of mechanochemical coupling, the kinetics and chemical equilibrium of the individual reaction steps comprising ATP hydrolysis on F1 inevitably in response to the gamma rotation | Bacillus sp. (in: Bacteria) | ? | - |
? | |
additional information | angle dependence of ATP or GTP binding and of hydrolysis, overview. Modulation of the high reversibility of mechanochemical coupling, the kinetics and chemical equilibrium of the individual reaction steps comprising ATP hydrolysis on F1 inevitably in response to the gamma rotation | Bacillus sp. (in: Bacteria) PS3 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
F1 | - |
Bacillus sp. (in: Bacteria) |
F1-ATPase | - |
Bacillus sp. (in: Bacteria) |
rotary molecular motor | - |
Bacillus sp. (in: Bacteria) |