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Literature summary for 7.1.2.2 extracted from

  • Bowler, M.W.; Montgomery, M.G.; Leslie, A.G.; Walker, J.E.
    How azide inhibits ATP hydrolysis by the F-ATPases (2006), Proc. Natl. Acad. Sci. USA, 103, 8646-8649.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.1.2.2

Crystallization (Commentary)

Crystallization (Comment) Organism
to 1.95 A resolution, crystals grown in the presence of ADP, 5'-adenylyl-imidodiphosphate and azide in microdialysis buttons, diffraction properties of crystals improved by controlled dehydration Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
azide interacts with the beta-phosphate of ADP and with residues in the ADP-binding catalytic subunit, occupying a position between the catalytically essential amino acids beta-Lys-162 in the P loop and the arginine finger residue alpha-Arg-373, tightens the binding of the side chains to the nucleotide, enhancing its affinity and thereby stabilizing the state with bound ADP Bos taurus
BeF3-
-
 Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Bos taurus 5739
-

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Synonyms

Synonyms Comment Organism
F1-ATPase
-
 Bos taurus