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Literature summary for 7.1.1.9 extracted from

  • Fontanesi, F.; Jin, C.; Tzagoloff, A.; Barrientos, A.
    Transcriptional activators HAP/NF-Y rescue a cytochrome c oxidase defect in yeast and human cells (2008), Hum. Mol. Genet., 17, 775-788.
    View publication on PubMed
Search for more literature for 7.1.1.9

Activating Compound

Activating Compound Comment Organism Structure
additional information overexpression of Hap4p, the catalytic subunit of the CCAAT binding transcriptional activator Hap2/3/4/5p complex, suppresses the respiratory defect of yeast shy1 mutants by increasing the expression of nuclear-encoded COX subunits that interact with the mitochondrially encoded Cox1p Saccharomyces cerevisiae
additional information overexpression of the NF-YA/B/C transcription complex in SURF1-deficient fibroblasts from an Leigh’s syndrome patient efficiently rescues their COX deficiency Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
overexpressed in DELTAshy1 strain Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Saccharomyces cerevisiae 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
Cu
-
 Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Saccharomyces cerevisiae
-
 strains W303-1A , DELTAshy1 and W125
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
COX
-
 Homo sapiens
COX
-
 Saccharomyces cerevisiae
cytochrome c oxidase
-
 Homo sapiens
cytochrome c oxidase
-
 Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
hemin
-
 Saccharomyces cerevisiae