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Literature summary for 7.1.1.8 extracted from

  • Ohsumi, K.; Watanabe, M.; Fujie, A.
    AS2077715 is a selective inhibitor of fungal mitochondrial cytochrome bc1 complex (2014), J. Antibiot., 67, 713-716 .
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
AS2077715 selective inhibitor, IC50 of 0.9 ng/ml Trichophyton mentagrophytes
funiculosin
-
Trichophyton mentagrophytes

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Trichophyton mentagrophytes 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ubiquinol + ferricytochrome c Trichophyton mentagrophytes
-
ubiquinone + ferrocytochrome c + H+
-
?

Organism

Organism UniProt Comment Textmining
Trichophyton mentagrophytes
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ubiquinol + ferricytochrome c
-
Trichophyton mentagrophytes ubiquinone + ferrocytochrome c + H+
-
?

Synonyms

Synonyms Comment Organism
cytochrome bc1 complex
-
Trichophyton mentagrophytes
ubiquinol-cytochrome c reductase complex III
-
Trichophyton mentagrophytes

Cofactor

Cofactor Comment Organism Structure
cytochrome c
-
Trichophyton mentagrophytes