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Literature summary for 7.1.1.8 extracted from

  • Spitkovsky, D.; Sasse, P.; Kolossov, E.; Bottinger, C.; Fleischmann, B.K.; Hescheler, J.; Wiesner, R.J.
    Activity of complex III of the mitochondrial electron transport chain is essential for early heart muscle cell differentiation (2004), FASEB J., 18, 1300-1302.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
antimycin A inhibits the enzyme complex and blocks the cell differentiation, inhibition mechanism Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Mus musculus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus activity of enzyme complex III of the mitochondrial electron transport chain is essential for early heart muscle cell differentiation ?
-
?
ubiquinol-2 + 2 ferricytochrome c Mus musculus
-
ubiquinone-2 + 2 ferrocytochrome c + 2 H+
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cardiac myocyte enzyme expression pattern during cell development Mus musculus
-
ES-D3 cell transgenic embryonic stem cell line with expression of the green fliuorescent protein under control of the alpha-myosin heavy chain promotor, enzyme expression pattern during cell development Mus musculus
-
heart
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information activity of enzyme complex III of the mitochondrial electron transport chain is essential for early heart muscle cell differentiation Mus musculus ?
-
?
ubiquinol-2 + 2 ferricytochrome c
-
Mus musculus ubiquinone-2 + 2 ferrocytochrome c + 2 H+
-
?

Synonyms

Synonyms Comment Organism
complex III
-
Mus musculus
cytochrome bc1 complex
-
Mus musculus