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Literature summary for 7.1.1.7 extracted from

  • Boot, M.; Jim, K.K.; Liu, T.; Commandeur, S.; Lu, P.; Verboom, T.; Lill, H.; Bitter, W.; Bald, D.
    A fluorescence-based reporter for monitoring expression of mycobacterial cytochrome bd in response to antibacterials and during infection (2017), Sci. Rep., 7, 10665 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
analysis development of a mCherry-based fluorescent reporter for detection of cytochrome bd expression in Mycobacterium marinum. The expression reporter is suitable for monitoring mycobacterial cytochrome bd expression during mouse macrophage infection and in a zebrafish embryo infection model Mycobacterium marinum

Organism

Organism UniProt Comment Textmining
Mycobacterium marinum B2HQZ0 and B2HQY9 B2HQZ0 i.e. subunit cydA, B2HQY9 i.e. subunit cydB
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Mycobacterium marinum ATCC BAA-535 B2HQZ0 and B2HQY9 B2HQZ0 i.e. subunit cydA, B2HQY9 i.e. subunit cydB
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Expression

Organism Comment Expression
Mycobacterium marinum expression is not induced by inhibitors of protein-, DNA- or RNA synthesis additional information
Mycobacterium marinum expression is induced by mycolic acid biosynthesis inhibitors such as isoniazid and especially by drugs targeting oxidative phosphorylation up