Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 7.1.1.3 extracted from

  • Thomas, J.W.; Lemieux, L.J.; Alben, J.O.; Gennis, R.B.
    Site-directed mutagenesis of highly conserved residues in helix VIII of subunit I of the cytochrome bo ubiquinol oxidase from Escherichia coli: an amphipathic transmembrane helix that may be important in conveying protons to the binuclear center (1993), Biochemistry, 32, 11173-11180.
    View publication on PubMed
Search for more literature for 7.1.1.3

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli RG129 cells Escherichia coli

Protein Variants

Protein Variants Comment Organism
K362L catalytically inactive Escherichia coli
K362M catalytically inactive Escherichia coli
K362Q catalytically inactive Escherichia coli
M353A the mutant shows substantial activity Escherichia coli
P358A the mutant shows substantial activity Escherichia coli
T352A catalytically inactive Escherichia coli
T352N the mutant shows substantial activity Escherichia coli
T352S the mutant shows substantial activity Escherichia coli
T359A catalytically inactive Escherichia coli
T359S the mutant shows almost wild type activity Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Escherichia coli 16020
-

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Escherichia coli GL101
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ubiquinol-1 + O2 + H+/in
-
 Escherichia coli ubiquinone-1 + H2O + H+/out
-
 ?
ubiquinol-1 + O2 + H+/in
-
 Escherichia coli GL101 ubiquinone-1 + H2O + H+/out
-
 ?

Synonyms

Synonyms Comment Organism
cytochrome bo ubiquinol oxidase
-
 Escherichia coli

Cofactor

Cofactor Comment Organism Structure
heme heme b562 Escherichia coli