Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-azido-ubiquinone-2 | - |
Bos taurus | |
6-amino-4-(4-tert-butylphenethylamino)quinazoline | - |
Bos taurus | |
6-azido-4-(4-iodophenethylamino)quinazoline | the compound specifically binds to the 49000 Da and ND1 subunits with a frequency of about 4:1 | Bos taurus | |
6-azido-N-[2-(4-tert-butylphenyl)ethyl]-6,7-dihydroquinazolin-4-amine | - |
Bos taurus | |
bullatacin | - |
Bos taurus | |
fenpyroximate | - |
Bos taurus | |
Piericidin A | - |
Bos taurus | |
pyridabene | - |
Bos taurus | |
rotenone | - |
Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Bos taurus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | P17694 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADH + H+ + ubiquinone-1 | - |
Bos taurus | NAD+ + ubiquinol-1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
complex I | - |
Bos taurus |
mitochondrial proton-pumping NADH-ubiquinone oxidoreductase | - |
Bos taurus |
NADH-ubiquinone oxidoreductase | - |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Bos taurus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0000023 | - |
temperature not specified in the publication, in 20 mM Tris-HCl, pH 7.4 | Bos taurus | 6-azido-N-[2-(4-tert-butylphenyl)ethyl]-6,7-dihydroquinazolin-4-amine | |
0.0000045 | - |
pH and temperature not specified in the publication | Bos taurus | 6-amino-4-(4-tert-butylphenethylamino)quinazoline |