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Literature summary for 7.1.1.2 extracted from

  • Dröse, S.; Zwicker, K.; Brandt, U.
    Full recovery of the NADH:ubiquinone activity of complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica by the addition of phospholipids (2002), Biochim. Biophys. Acta, 1556, 65-72.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
asolectin activation by detergent solubilized asolectin Yarrowia lipolytica

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrial membrane
-
Yarrowia lipolytica 31966
-

Organism

Organism UniProt Comment Textmining
Yarrowia lipolytica
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
lipoprotein the phospholipid content varies between 26 and 66 mol phosphate per mol of complex in different batches. Complex 1 purified by affinity chromatography can be fully reactivated by returning phosphatidylcholine, phosphatidylethanolamine and cardiolipin, the phospholipids removed by the purification procedure Yarrowia lipolytica

Purification (Commentary)

Purification (Comment) Organism
-
Yarrowia lipolytica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADH + n-decylubiquinone + H+
-
Yarrowia lipolytica NAD+ + n-decylubiquinol
-
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Synonyms

Synonyms Comment Organism
complex 1
-
Yarrowia lipolytica
NADH:ubiquinone oxidoreductase
-
Yarrowia lipolytica

Cofactor

Cofactor Comment Organism Structure
additional information the enzyme contains only substoichiometric amounts of ubiquinone-9, 0.2-0.4 mol/mol Yarrowia lipolytica